Wednesday, June 3, 2009

Human olfactory psychophysics

This is a mainstream research paper about the sense of smell and is probably the current viewpoint of the mainstream on the olfactory system. It mentions concepts such as 'specific anosmia', 'threshold', and 'adaptation'. 'Specific anosmia' is the genetic inability to smell specific smells. Fecal body odor sufferers (or other bowel smells or other odd smells) often say they cannot smell themselves. This also seems to be the general rule for people with external body odor. However, those with fecal body odor can smell feces odor from other sources (not through human skin, it seems), so specific anosmia doesn't seem to be the reason. The same seems true for trimethylaminuria and probably other metabolic body odors, although Dr John Cashman reckons perhaps 8% cannot smell trimethylamine, although it's not known if he means only from humans or from any source. for example, most people seem to be able to smell fish. Another theory for this is 'adaptation' and desensitivity to the smell. This seems more likely than specific anosmia, however, perhaps sufferers have been in situations where a group of strangers complain of a smell but one stranger says they can't smell anything (for instance in school). Adaptation and desensitivity do not seem to account for this. At the moment it is a mystery. the most likely guess is that there is some genetic aspect, as of yet unknown.

That aside, the article is seemingly the 'latest' (2004) in olfactory perception and worth a read

Human olfactory psychophysics
Andreas Kellera and Leslie B. Vosshall 2004




Related Posts by Categories




0 comments:

Admin Control Panel

New Post | Settings | Change Layout | Edit HTML | Edit posts | Sign Out

Search This Blog

Loading...

Latest comments

Latest posts

Get daily update by email

Enter your email address:

Delivered by FeedBurner

You will be sent a verification email. Please click on the verification link on the email. If you do not receive an email, please check your spam folder.

 Subscribe in a reader

Regular FREE (long distance call plan) General and Women-only Phone Conferences

USA : (712) 432 1620
access code : 391629#
NON USA : add 001 prefix
General Conferences: normally every other Sunday at 2pm EDT.
Next call : Sunday February 21th : 2pm EDT

Scroll down for next Women's conference
Women's Conferences: normally every other Thursday 8.30pm EDT. Next call: October 29th at 8:30p.m. EDT


Arranged by the leaders of the bodyodorsupport.com forum

Note: can also be used anytime for unscheduled group chats

Free USA-based phone conferences (if you have a long distance call plan. Otherwise you will be charged as a long-distance call)

For USA-based : (712) 432 1620 then type the access code on your phone keypad: 391629#
Non USA : prefix above with 001 but check to see if it is free with your supplier


Record number of callers : 70+
If privacy is a concern, code your phone to PRIVATE mode
This phoneline can be used anytime to talk to other sufferers
You don't need to talk. You can just listen

Meet-up/Support group contacts

UK : Arun Nagrath: arunnagrath@hotmail.com
Miami : Maria: mpdela1@gmail.com

Action plans

Write an essay on your odor problem for Richards anthology project
contact your Senator about blood-borne BO/halitosis
write to 'the Doctors' TV show
contact the DrHoffman show on WOR710
tell the Office of Rare Diseases about your problem
try the asparagus urine test
Fecal Body Odor Volunteer for media appearances ?
Politicians ?
Ask an expert if they will put up a Q&A section on their websites like Emory have

suggestions

Thinktank

Bluesky ideas to promote thought:

PTC124(Ataluren, or similar) for primary TMAU due to nonsense mutations
Genetically modified probiotics enriched with FMO3 ?
Trimethylamine strip test paper for daily urine testing? (possibly used in the fish industry ?)
BO&Halitosis research center
BO&Halitosis research fund
Can FMO enzyme be induced in a helpful manner ?
Ask an expert if they will put up a Q&A section on their websites like Emory have
BO&Halitosis 'rehab' retreat (?)
TMAU cookbook/advice book
Employ an expert to do the most thorough choline list
Employ Body odor/halitosis expert(s) (?)
Encourage breath-analysis manufacturers to make portable handy analyzers for metabolic odor problems
TMA urine dipstick test
Is trimethylamine an FMO3 inhibitor ?
Campaign : add TMAU to the newborn screening program
Orphan drug program

Send in your ideas or post them on the forums: Contact experts